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2-Aminoethyl diphenylborinate

2-Aminoethyl diphenylborinate
2-Aminoethyl diphenylborinate (2-APB) is a chemical compound that inhibits IP3 receptors and TRP channels, though it activates TRPV1, TRPV2, and TRPV3 at higher concentrations.
Catalog No. T4693Cas No. 524-95-8
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Purity:99.92%
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2-Aminoethyl diphenylborinate

Catalog No. T4693Cas No. 524-95-8
2-Aminoethyl diphenylborinate (2-APB) is a chemical compound that inhibits IP3 receptors and TRP channels, though it activates TRPV1, TRPV2, and TRPV3 at higher concentrations.
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Pack SizePriceAvailabilityQuantity
10 mg$30In Stock
25 mg$65In Stock
50 mg$92In Stock
100 mg$129In Stock
500 mg$319In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Product Introduction

Bioactivity
Description
2-Aminoethyl diphenylborinate (2-APB) is a chemical compound that inhibits IP3 receptors and TRP channels, though it activates TRPV1, TRPV2, and TRPV3 at higher concentrations.
Targets&IC50
IP3:42 μM
Alias2-Aminoethoxydiphenyl borate, 2-APB
Chemical Properties
Molecular Weight225.09
FormulaC14H16BNO
Cas No.524-95-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (244.35 mM), Heating is recommended.
Ethanol: 10 mM, Heating is recommended.
5% DMSO+95% Saline: 1.13 mg/mL (5 mM)
Solution Preparation Table
5% DMSO+95% Saline/Ethanol/DMSO
1mg5mg10mg50mg
1 mM4.4427 mL22.2133 mL44.4267 mL222.1334 mL
5 mM0.8885 mL4.4427 mL8.8853 mL44.4267 mL
Ethanol/DMSO
1mg5mg10mg50mg
10 mM0.4443 mL2.2213 mL4.4427 mL22.2133 mL
DMSO
1mg5mg10mg50mg
20 mM0.2221 mL1.1107 mL2.2213 mL11.1067 mL
50 mM0.0889 mL0.4443 mL0.8885 mL4.4427 mL
100 mM0.0444 mL0.2221 mL0.4443 mL2.2213 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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